Last edited by Sazshura
Tuesday, April 28, 2020 | History

6 edition of Drug Delivery to the Oral Cavity found in the catalog.

Drug Delivery to the Oral Cavity

Molecules to Market (Drugs and the Pharmaceutical Sciences)

by

  • 144 Want to read
  • 29 Currently reading

Published by Informa Healthcare .
Written in English

    Subjects:
  • Pharmacology,
  • Oral mucosa,
  • Medical,
  • Medical / Nursing,
  • Engineering - General,
  • Medical / Pharmacology,
  • Biochemistry,
  • Oral medication

  • Edition Notes

    ContributionsTapash K. Ghosh (Editor), William Pfister (Editor)
    The Physical Object
    FormatHardcover
    Number of Pages448
    ID Numbers
    Open LibraryOL8126297M
    ISBN 100824782933
    ISBN 109780824782931

    Oral squamous cell carcinoma (OSCC), which encompasses the oral cavity-derived malignancies, is a devastating disease causing substantial morbidity and mortality in both men and women. It is the most common subtype of the head and neck squamous cell carcinoma (HNSCC), which is ranked the sixth most common malignancy worldwide. Despite promising advancements in the conventional Cited by: 1. Drug should be partially unionized at oral cavity pH. Drug should have small molecular size and low molecular weight. Drug molecule should have the capability to permeate oral mucosa4. Advantages of Fast Dissolving Films: Improved oral bioavailability of drug as hepatic first pass effect is Size: 1MB. An accessible and easy-to-read textbook, Drug Delivery and Targeting for Pharmacists and Pharmaceutical Scientists is the first book to provide a comprehensive introduction to the principles of advanced drug delivery and targeting, their current applications and potential future developments, including:*Methods to optimize therapeutic efficacy 5/5(1).


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Drug Delivery to the Oral Cavity Download PDF EPUB FB2

Drug Delivery to the Oral Cavity PDF Drug Delivery to the Oral Cavity PDF Free Download Drug Delivery to the Oral Cavity PDF Drug Delivery to the Oral Cavity Ebook Content Drug Delivery to the Oral Cavity book oral cavity (OC) and its highly permeable mucosal tissues have been taken advantage of.

Buy Drug Delivery to the Oral Cavity: Molecules to Market (Drugs and the Pharmaceutical Sciences Book ): Read Kindle Store Reviews - ufacturer: CRC Press. Book Description. With contributions from recognized authorities in industry, academia, and government, this reference presents the state-of-the-art Drug Delivery to the Oral Cavity book the testing, formulation, and clinical evaluation of intraoral drug delivery products-summarizing intraoral dosage forms in various stages of research, as well as products currently on the market.

Drug Delivery Drug Delivery to the Oral Cavity book the Oral Cavity: A Focus on Mucoadhesive Buccal Drug Delivery Systems Article (PDF Available) September with 2, Reads How we measure 'reads'. Drug Delivery to the Oral Cavity: Molecules to Market (Drugs and the Pharmaceutical Sciences): Medicine & Health Science Books @ ce: $ Drug delivery systems (DDSs) are pharmaceutical formulations or devices that help in achieving targeted delivery and/or controlled release (CR) of therapeutic agents in our body [].Following administration, the DDSs liberate the active ingredients, and subsequently, the bioactive molecules are transported across various biological barriers to reach the site of by: 4.

The oral drug-delivery system has been believed and proved for decades, to be advantageous over any other novel drug-delivery systems (NDDS). An oral drug delivery system is thus believed to provide continuous oral release of the drug throughout the course of its gastrointestinal (GI) transit.

Dental drug delivery systems have been used for a long time, in particular for the local therapy of diseases affecting the oral cavity. Research today concentrates on the design of formulations to Drug Delivery to the Oral Cavity book their retention time.

Even today, however, prosthetic devices incorporating drug delivery are rarely by: ISBN: OCLC Number: Description: xix, pages: illustrations ; 24 cm. Series Title: Drugs and the pharmaceutical sciences. Umesh Gupta, Omathanu Perumal, in Natural and Synthetic Biomedical Polymers, Oral Drug Delivery.

Oral drug delivery is the most preferred drug administration route due to convenience, cost-effectiveness, and high patient compliance. The challenges in oral drug delivery include aqueous solubility, membrane permeability, and chemical and enzymatic stability of Drug Delivery to the Oral Cavity book.

A Review on Oral Mucosal Drug Delivery System Rakesh Hooda*, Mohit Tripathi and Prof. Kiran Kapoor Submitted Accepted for publication Buccal controlled drug delivery system has been developed since the environment of the oral cavity provides potential sites for drug delivery. The acid hydrolysis and first pass effects can be.

CONCLUSION Buccal drug delivery is a promising area for continued research with the aim of systemic delivery of orally inefficient drugs, as well as a feasible and attractive alternative for non-invasive delivery of potent peptide and protein drug molecules. Azo polymeric new drug In which use of polymers as drug carriers for drug delivery to colon.

Synthetic, naturally, sub-synthetic polymers used form colon targeted polymeric prodrug with azo linkage between polymer & drug moiety. The various azo polymers are evaluated for coating materials over drug are susceptible to cleavage by azo.

Find many great new & used options and get the best deals for Drugs and the Pharmaceutical Sciences: Drug Delivery to the Oral Cavity: Molecules to Market (, Hardcover) at the best online prices at eBay.

Free shipping for many products. Fast dissolving oral drug delivery system are solid dosage form which disintegrate or dissolve within seconds when placed in the mouth without need of water or chewing.

Get this from a library. Drug delivery Drug Delivery to the Oral Cavity book the oral cavity: molecules to market. [Tapash K Ghosh; William R Pfister;] -- With contributions from recognized authorities in industry, academia, and government, this reference presents the state-of-the-art in the testing, formulation, and clinical evaluation of intraoral.

Free Download of Design of Controlled Release Drug Delivery Systems pdf e-book. Edited By Xiaoling Li & Bhaskara R. Jasti. To Download this book click on the following image or link:Author: Pharmatech. Drug delivery from the oral cavity: a focus on mucoadhesive buccal drug delivery systems.

Shinkar DM(1), Dhake AS, Setty CM. Author information: (1)Department of Pharmaceutics, KCT'S RGS College of Pharmacy, Anjaneri, Nashik, Maharashtra, by: The book describes the anatomical and physiological challenges of this route for drug delivery and how they impact the design of oral mucosal drug delivery systems.

It also provides a detailed description of current oral mucosal drug delivery technologies that overcome these challenges alongside research, development and assessment methods. Iontophoresis is a noninvasive method to enhance systemic and local drug delivery by the application of an electric field.

For systemic drug delivery in the oral cavity, iontophoresis was studied primarily for transbuccal delivery. Significant enhancement of drug delivery was observed in buccal iontophoresis compared to passive transport for different by: 2.

Drug Delivery to the Oral Cavity: Molecules to Market With contributions from recognized authorities in industry, academia, and government, this reference presents the state-of-the-art in the testing, formulation, and clinical evaluation of intraoral drug delivery products-summarizing intraoral dosage forms in various stages of research, as well as products currently on the market.

Among the various routes of the drug delivery, oral way is mostly favored by the patients and preferred by the clinicians. However, peroral (Jain. al., ) administrations of drugs have drawbacks such as hepatic first-pass metabolism and enzymatic degradation within the GI, which thus prohibits dental supervision of certain classess of drugs.

Drug Delivery to the Oral Cavity: Molecules to Market (Drugs and the Pharmaceutical Sciences) Tapash K. Ghosh, William Pfister. With contributions from recognized authorities in industry, academia, and government, this reference presents the state-of-the-art in the testing, formulation, and clinical evaluation of intraoral drug delivery.

Oral infections. A healthy oral cavity is normally colonized by fungi, viruses and bacteria with the latter predominating. It has been estimated that over bacterial species reside in the oral cavity; some may be pathogenic, others are symbiotic or commensal [10,11].When the normal flora of the mouth is disrupted, for example, with tobacco use, pregnancy, diet, nutrition, age and oral Cited by:   Thus, drug delivery to the oral cavity should be diversified, as the pathogens and pathogenicity have many faces and modes of action.

In this chapter, various pathogens and numerous drug delivery systems are presented, and a growing trend in Cited by: 2. Nanocarriers for drug delivery.

Nanomedicine is a rapidly developing area that is revolutionizing cancer diagnosis and therapy. Nanoparticles Cited by: Drug Delivery to the Oral Cavity Edited by Tapash K.

Gosh and William Pfister. Drug Delivery to the Oral Cavity emphasizes the impact of intraoral drug delivery and its advantages over conventional oral dosage forms. Features. Covers the latest research concerning drug delivery to the oral cavity, and examines the basic structure, function, biochemistry, and permeability of the oral cavity.

Oral Controlled Drug Delivery Systems Oral controlled release drug delivery is a system that provides continuous oral delivery of drugs at predictable and reproducible kinetics for a predetermined period throughout the course of GI transit and also the system that target the delivery of a drug to a specific.

advanced drug delivery systems to the oral cavity is on-going. The present review will focus on recent advances in the local treatment and prevention of the most preva - lent oral diseases and conditions.

In the first part, novel drug delivery systems for oral infections, including dental caries, periodontitis and oral mucosal infections. Ebooks list page: ; Drug Delivery to the Oral Cavity; Encyclopedia of Controlled Drug Delivery, 2 Volume Set; Polymeric Drugs and Drug Delivery Systems by Raphael M.

Ottenbrite; Premalignant Conditions of the Oral Cavity (Head and Neck Cancer Clinics); Premalignant Conditions of the Oral Cavity; Premalignant Conditions. The oral cavity is a complex environment for drug delivery as there are many interdependent and independent factors which reduce the absorbable concentration at the site of absorption[25].

Membrane Factors: This involves degree of keratinization, surface area available for absorption, mucusCited by: placed the solution in the topic ‘s oral cavity. The basic drug solution of changing pH was circulated about times by the motion of the cheeks and lingua for a contact clip of 5 min.

The solution was so expelled, and the voluntary ‘s oral cavity was rinsed with 10 milliliters distilled H2O for 10 s. Thin-film drug delivery uses a dissolving film or oral drug strip to administer drugs via absorption in the mouth (buccally or sublingually) and/or via the small intestines (enterically).A film is prepared using hydrophilic polymers that rapidly dissolves on the tongue or buccal cavity, delivering the drug to the systemic circulation via dissolution when contact with liquid is made.

Successful mucosal administration and delivery of drugs still pose a great challenge. However, the possibility to deliver not only small drug molecules but also macromolecular drugs and nanoparticles via mucosal surfaces represents a great opportunity. Rapid onset of drug action, avoidance of first-pass metabolism, and high immunocompetence of mucosa are some of the important features for Author: Josef Mašek, Eliška Mašková, Daniela Lubasová, Roman Špánek, Milan Raška, Jaroslav Turanek.

The book discusses the anatomy and physiology of administration sites; the formulation and design of delivery systems; and other relevant aspects of biopharmaceutics. The text describes pulmonary delivery, nasal, buccal, and transdermal routes of administration for systemic delivery, as well as a number of systems for more localized therapy Book Edition: 1.

Anatomy and Physiology of the Oral Cavity. Local Diseases of the Oral Cavity. Permeability of the Buccal and Gingival Mucosa. Drug Delivery Systems for the Oral Cavity. Formulations. Conclusions. ReferencesCited by: 4. By Kalliopi Dodou. In this month’s science article, Kalliopi Dodou examines the pharmaceutics behind buccal and sublingual drug delivery and looks at new developments in this area Oral administration of medicines still enjoys a hallowed place in drug delivery systems and, unsurprisingly, still takes the lion’s share of the pharmaceuticals marketplace.

Anatomy of the oral cavity. The oral cavity includes the lips, hard palate (the bony front portion of the roof of the mouth), soft palate (the muscular back portion of the roof of the mouth), retromolar trigone (the area behind the wisdom teeth), front two-thirds of the tongue, gingiva (gums), buccal mucosa (the inner lining of the lips and cheeks), and floor of the mouth under the tongue.

Drug delivery refers to approaches, formulations, technologies, and systems for transporting a pharmaceutical compound in the body some time based on nanoparticles as needed to safely achieve its desired therapeutic effect. It may involve scientific site-targeting within the body, or it might involve facilitating systemic pharmacokinetics; in any case, it is typically concerned with both.

INTRODUCTION: Oral mucosal drug delivery system is subdivided into buccal and sublingual in which buccal cavity is widely applicable for drug administration through mucosa in case of sublingual route mostly useful for fastest onset of action as in the case of Angina buccal mucosa lines the inner cheek, and buccal formulations are placed in the mouth between the upper gingivae.

Buccal drug delivery system: Buccal drug delivery system The buccal cavity offers many pdf for drug delivery application. Additionally, buccal drug delivery can be promptly terminated in cases of toxicity through the removal of dosage form thereby offering a safe and easy method of drug utilization.

Monday, Febru BUCCAL DRUG DELIVERY SYSTEM. Oral mucosa: Anatomy of the download pdf mucosa Light microscopy reveals several distinct patterns of maturation in the epithelium of the human oral mucosa based on various regions of the oral cavity.

Three distinctive layers of the oral mucosa are: * the epithelium, * basement membrane, and * connective tissues.Ebook aim of the Journal is to provide a forum for the critical analysis of advanced drug and gene delivery systems and their applications in human and veterinary medicine.

The Journal has a broad scope, covering the key issues for effective drug and gene delivery, from administration to site-specific delivery.